Также известен как: Breezula, CB-03-01, Winlevi (acne formulation)
First-in-class topical androgen receptor antagonist; FDA-approved for acne, in trials for AGA.
Clascoterone is a topical androgen receptor (AR) inhibitor that competes with DHT for AR binding directly at the follicle. Unlike systemic anti-androgens, it is metabolized locally to cortexolone, minimizing systemic exposure. It blocks androgen signaling at the receptor level rather than reducing DHT production.
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